Diabetes Mellitus

Definition (Diabetes Care 2019;42:S13)

  • Either HbA1c ≥6.5, fasting glc ≥126 mg/dL, or glc 2 h after OGTT ≥200 mg/dL × 2 (for any test) or single random glc ≥200 mg/dL w/ classic sx of hyperglycemia; all tests equally reasonable (nb, may be ⊕ on one test but not another); OGTT preferred during preg
  • Blood glc higher than normal, but not frank DM (“prediabetics,” ~40% U.S. population)
    • HbA1c 5.7–6.4%, impaired fasting glc (IFG) 100–125 mg/dL, or 2 h prandial glc 140–199
    • Preventing progression to DM: diet & exercise (58% metformin (31% ↓;