Tick-Borne Diseases

Distinguishing Features of Tick-Borne Illnesses
Disease Rash ↓ WBC Anemia ↓ Plts ↑ LFTs
Lyme 80%: erythema migrans +
RMSF 90%: petechiae, palms/soles + + +++
Borrelia miyamotoi <10% ++ + +++ +++
Ehrlichiosis (HME) 25%: maculopapular, petechiae +++ ++ ++++ ++++
Anaplasmosis (HGA) <5% +++ + +++ ++++
Babesia + ++++ (lysis) ++++ +++

–: <15%, +: 15–25%, ++: 25–50%, +++: 50–75%, ++++: >75%

Lyme Disease

Microbiology

  • Spirochete B. burgdorferi (consider coinfection w/ Anaplasma, Babesia, B. miyamotoi)
  • Transmitted by ticks (Ixodes, deer ); infxn usually requires