Bacteremia & Endocarditis
1° infxn due to direct inoculation of the blood, frequently assoc w/ intravascular catheters. Catheter-related bloodstream infection = same org from peripheral cx and cath tip cx or cx drawn from catheter (CID 2009;49:1).
2° infxn due to infection in another site (eg, UTI, lung, biliary tree, skin) spreading to blood
Coag-neg staph 34%, S. aureus 10%, enterococci 16%, Candida 12%, GNRs 5%
Clostridium septicum, Bacteroides, & S. bovis a/w colon ca (Gastro 2018;155:383)
Bacteremia with encapsulated organisms (S. pneumo, Neisseria, Haemophilus, strep) may indicate 1° immunodeficiency (