Soft Tissue and Bone Infections

Skin and Soft Tissue Infections (SSTI; CID 2014;59:10)


  • Cellulitis: infxn of dermis/sc fat, w/ erythema, edema, warmth, pain (rubor, tumor, calor, dolor)
  • Erysipelas: infxn of upper dermis (more superficial than cellulitis), often caused by strep, w/ raised erythematous lesion w/ clear demarcation from normal skin
  • Impetigo: infxn of superficial layers, often caused by staph, typically in children, w/ purulent lesions, often on face/extrem, ± bullae, ± gold crust
  • Lymphangitis: proximal red streaking ± regional lymphadenopathy
  • Toxic shock syndrome can occur w/ staph or strep infxn. Fever, HA, N/V, diarrhea, myalgias, s, diffuse rash w/ desquamation, HoTN, shock. BCx may be ⊖.