Hepatic Vascular Disease

Figure 3-6 Normal hepatic vasculature
Modified from The Nature of Disease Pathology for the Health Professions, 2007. Hepatology 2009;49: 1729.

Portal vein thrombosis (PVT) (Clin Liver Dis 2017;10:152)

  • Definition: thrombosis, constriction or invasion of portal vein; may lead to portal HTN
  • Etiologies: cirrhosis, neoplasm (pancreas, HCC), abdominal infxn, hypercoag states (qv), pancreatitis, collagen vascular diseases, Behçet’s, IBD, surgery, trauma, OCPs, preg
  • Clinical manifestations
    • acute: can p/w abd or lumbar pain, or asx w/ incidental finding on U/S or CT. If mesenteric vein involved may p/w intestinal rct. If fever, consider pylephlebitis.