• Alias: KB-145911
    • Small-molecule inhibitor of porcupine (PORCN) protein, important for Wnt pathway signaling
    • Currently in phase 1 clinical trials for malignancies dependent on Wnt ligands, including melanoma, breast cancer, and pancreatic adenocarcinoma
    • No published clinical results
    (Liu et al., 2013)
    Other topics in Targeted and Immunotherapy Agents